Protein Details: Short transient receptor potential channel 6

Protein ID

ICDB_Pro_1566

Protein Name

Short transient receptor potential channel 6

Gene Name

TRPC6; TRP6

Organism

Bos taurus (Bovine)

Length

931 amino acids

AlphaFoldDB

AF-Q9MYW0-F1-model_v4.pdb

Function

Sequence

MNQSPAAFGPRRGGSPAVVAGAGARRNESQDYLLMDSELGDDAQPPLPAYGYYPCLRGTDSRLTHRRQTVLREKGRRLANRGPAYMFNDHSTSLSIEEERFLDAAEYGNIPVVRKMLEECLSLNVNCVDYMGQNALQLAVANEHLEITELLLKKENLSRVGDALLLAISKGYVRIVEAILSHPAFAEGKRLATSPSQSELQQDDFYAYDEDGTRFSHDVTPIILAAHCQEYEIVHTLLRKGARIERPHDYFCKCSECNQKQKHDSFSHSRSRINAYKGLASPAYLSLSSEDPVMTALELSNELAVLANIEKEFKNDYKKLSMQCKDFVVGLLDLCRNTEEVEAILNGDVEIHHSGGDHYRPNLSRLKLAIKYDVKKFVAHPNCQQQLLSIWYENLSGLRQQTMAVKFLVVLAVAVGLPFLALVYWFAPCSKMGKIMRGPFMKFVAHAASFTIFLGLLVMNAADRFEGTKILPNETSTDHAKQLFRMKTSCFSWMEMLIISWVIGMIWAECKEIWTQGPKEYLFELWNMLDFGMLAIFAASFIARFMAFWHASKAQSIIDANDTLKDLTKVTLGDNVKYYNLARIKWDPSDPQIISEGLYAIAVVLSFSRIAYILPANESFGPLQISLGRTVKDIFKFMVIFIMVFVAFMIGMFNLYSYYIGAKQNEAFTTVEESFKTLFWAIFGLSEVKSVVINYNHKFIENIGYVLYGVYNVTMVIVLLNMLIAMINSSFQEIEDDADVEWKFARAKLWFSYFEEGRTLPVPFNLVPSPKSLFYLLLRLKKWISELFQGHKKGFQEDAEMNKRNEGKKFGILGSHEDLSKLSLDRKQFAHSKQSSIRSSEDFQLNSFTNPPRQYQKIMKRLIKRYVLQAQIDKESDEVNEGELKEIKQDISSLRYELLEEKTQNSEDLAELIRKLGEKLSMEPNQEESNR

PDB Structures

Ligand Binding

1. DICL_CP

2. DICL_Pep

Binding Site

Disease

Location

DOI ID

10.1186/gb-2009-10-4-r42; 10.1074/jbc.m003408200

RefSeq

NP_001160044.1; XP_015330068.1